Tools
PanRV
PanRV is a Linux based software package in JAVA language that uses both pangenome and reverse vaccinology approaches. It has four modules: Pangenome Estimation (PGM), Reverse Vaccinology (RVM), Functional Annotation (FAM), and Antibiotic Resistance Association (ARM).
VacSol
VacSol a high throughput in silico pipeline to predict potential therapeutic targets in prokaryotic pathogens using subtractive reverse vaccinology
B-Pan
B-pan is the updated version of PanRV, a software package that employs both pangenome and reverse vaccinology approaches. Beyond conventional pan-genome analyses, B-Pan integrates functional annotations (COGs) and algorithms for phylogenetic and evolutionary analysis.
B-vac
B-vac is an updated version of VacSol, a high-throughput computational pipeline for predicting potential therapeutic targets in prokaryotic pathogens using the subtractive reverse vaccinology approach. Written in Python, B-vac builds upon the strengths of its predecessor, VacSol, and offers improved functionality and ease of use for the prediction of vaccine targets in bacterial pathogens.
VacSol-ML(ESKAPE)
VacSol-ML is a web-based tool that uses machine learning algorithms to predict potential vaccine candidates in ESKAPE pathogens, which are a group of bacteria that have been identified as causing significant challenges in healthcare. By using high-throughput, in silico analysis, VacSol-ML aims to speed up the process of identifying potential vaccine candidates and help address the growing problem of antibiotic resistance.
AbAMPdb
AbAMPdb is the manually-curated database for antimicrobial peptides (AMPs) specifically against Acinetobacter baumannii. The database provides information related to antimicrobial potentials, homology-based modelled structures and the peptide-protein interactions of these AMPs.